Here are the big stories on the agenda today:

A Catholic high school at the center of the H1N1 flu outbreak will reopen today, after a top-to-bottom scrubbing, but how many students will show?  There have been 59 confirmed H1N1 cases and two dozen more suspected at St. Francis Prep in Queens, the biggest outbreak in the country.  There’s also doubt about whether “patient zero,” a five-year-old Mexican boy, is really the source.  There are mixed and powerful opinions about closing the border with Mexico during this outbreak.  We want to hear yours.  Call us at 877-MYAMFIX, or throw your thoughts up on twitter @MYAMFIX.

Breaking this morning… President Obama's tax reform push.  The president is set to roll out a series of tax reform proposals that could change the way this country does business overseas.

The McCanns speak.  In their first interview in the United States, Kate and Gerry McCann, parents of missing child Madeleine McCann join Oprah to discuss the two-year search for their daughter, how their family is coping, and what it has been like to be vilified all over the world.   Madeleine’s disappearance from a family vacation in Portugal on May 3, 2007 has made international headlines.  Now, viewers around the globe will see what Madeleine might look like as a six-year-old, through a remarkable age progression image.

Making the Grand ol’ Party new.  Veteran Pennsylvania Senator Arlen Specter said Sunday that he hopes his switch to the Democratic Party will serve as a "wake-up call" to an increasingly conservative GOP.  We’ll speak to Congressman Eric Cantor, (R-VA) who started the National Council for a New America to rebuild the Republican image. They had their first meeting on Saturday at a pizza place in Arlington, Virginia. Mitt Romney and Jeb Bush were among the speakers. Did these leaders find the way forward?

With Myspace friends like these… Two employees of Houston’s Restaurant in New Jersey lost their jobs after their employer logged on to an invite-only discussion group on MySpace and read negative comments they made about work. They weren’t at work.  They weren’t using a work computer.  Should the boss butt out?