South Korean protesters burn anti-North Korea signs during a protest in Seoul on May 25, 2009 in response to the communist country's claim it conducted a nuclear test.

Here are the big stories on the agenda this Memorial Day:

• Breaking overnight… North Korea announces it has “successfully” carried out an underground nuclear test and reportedly test-fired a short-range, ground-to-air missile.  The world-wide resources of CNN will bring you reaction from Beijing to Washington.   The Chairman of the Joint Chiefs, Admiral Mike Mullen will join us live with his response to what the White House is calling a “threat to international peace and security.”
• Now it’s his turn.  On this Memorial Day weekend, the man who is arguably America’s most popular living general fired back.  Former Secretary of State Colin Powell insists he's still a republican, no matter what Dick Cheney says.
• Dad’s clock, tick-toc.  When you hear the term "biological clock," you probably think of women, because women are often the ones who worry about the impact of age on pregnancy, but now there's a new study that says men might want to move things along a little faster.
• Same-sex marriage limbo.  Tomorrow will be a landmark day in the battle for gay rights, as California’s Supreme Court rules on the legality of Proposition Eight, which banned same-sex marriage in California and made it illegal.  Our Ted Rowlands is with one couple we first met on the courthouse steps, minutes after they got married.  Now they're anxiously waiting to find out if that marriage means anything at all.
• His life is a movie script in the making.  Helio Castroneves won his third Indianapolis 500 on Sunday, the ultimate triumph after facing deportation and prison time a little over a month ago.  Now all charges are dropped, he’s on top of his sport again and will join us live.

Here are the big stories on the agenda today:

The Senate sending the White House a message, approving a $91-billion bill to fund the wars in Iraq and Afghanistan, but refusing to authorize any spending on President Obama's plan to close Guantanamo Bay prison.   This comes after the present collided with the past, over the best way to protect you.  President Obama and former Vice President Dick Cheney clashed over closing Gitmo, harsh interrogation policies and other approaches to fighting terrorism, as they delivered dueling speeches in which they both pointed fingers and forcefully defended their respective policies.  Supporters on both sides are loud.  Opinions are strong.  We’ll hear from Liz Cheney, a former State Department official who says her father is on the right side of history.  We want you to join the debate, too.  Call us at 877-MYAMFIX.

We're also following developments in the life-and-death search for a cancer-stricken teenager and his mother.  Authorities in Minnesota have issued a felony arrest warrant for Colleen Hauser, who fled with her 13-year-old son Daniel to avoid court-ordered chemotherapy treatments.  The warrant allows other states to detain the pair if they're found.  It's believed mother and son may be headed to Mexico for an alternative treatment for the boy’s Hodgkin’s Lymphoma.  Doctors say without chemotherapy, Daniel's chances of survival are slim, and his father is making a public appeal to his wife to return with their son.

And… who are the “wingnuts” of the week?  John Avlon is here to expose those on the far left and right who are pulling this country further apart.

Hello everyone,

We're following several developing stories right now. We'll break them down for you this morning.

Here are the big stories on the agenda today:

• Breaking news. A New York City hospital says a 16 month-old-boy died there late last night with flu-like symptoms. The CDC is coming in to determine if the baby had swine flu. People in masks were packing the waiting room there yesterday.  We're live outside the hospital.
• President Obama today announcing a national standard for car emissions – a tough new assault on greenhouse gasses. The administration is expected to require new cars or trucks be 30% "cleaner" and more fuel efficient by 2016. The CNN Money Team is breaking down what that means for your next buy and for the struggling auto industry's bottom line.
• CIA Director Leon Panetta says he's confident Pakistan has a "pretty secure" nuclear arsenal, even though the U.S. doesn't know the exact location of all its warheads. It's something U.S. Intel is watching closely with Pakistan at war with the Taliban.
• Donald Rumsfeld revealed.  Accusations that he botched everything from the battle for hearts and minds – to the response to Katrina.  GQ Magazine says it’s obtained top-secret Iraq war documents that contain biblical passages on the cover sheets.  How much damage did the former defense chief really do to his boss's legacy?  We'll talk to the reporter who broke this story.
• Saying goodbye to the Hubble telescope – for good.  Astronauts on Space Shuttle Atlantis will gently toss it back into earth’s orbit this morning, after five successful spacewalks to repair it.  Human hands will never touch it again.  NASA hopes the repairs will allow Hubble to keep exploring the universe until it's replaced in 2014.
• Hoping for another strong sign that the economy has "bottomed out."  Monthly data on new home construction is due out before the start of trading today.  The CNN  Money Team will be here to break down the numbers at 8:30 eastern.

Here are the big stories on the agenda today:

• The damage being described as "unbelievable" in one Missouri town – where a killer tornado touched down last night.  See an iReporter’s view of the massive funnel cloud.
• Sadness turning into anger and frustration, in day two of hearings into the deadly plane crash outside Buffalo, New York.  Family members want to know why their loved ones lives were in the hands of a pilot – who may not have gotten enough sleep or training.
• The mission to fix the eye that sees through time.  The crew of Space Shuttle Atlantis takes the first of five risky spacewalks to repair the Hubble Telescope.  We'll have the pictures from space live.
• After weeks of pressure from state and local law enforcement officials, Craigslist, the most popular classifieds site on the web, is getting rid of its controversial "erotic services" section.  Police say a medical student accused of murdering a masseuse – found her there.  Hear John Roberts’ exclusive interview with Craigslist CEO Jim Buckmaster.